Boron
Also known as: Boric acid, Boron citrate, Calcium fructoborate, Sodium borate
The bone-and-joint trace mineral — small trials, a calcium-magnesium-vitamin D partnership, and a 20 mg upper limit.

Boron affects mineral metabolism, but human evidence for bone, osteoarthritis, or hormone outcomes is limited and there is no established U.S. recommended intake. Small calcium-fructoborate trials should not be generalized to every boron supplement.1, 2
- Trace mineral found in plant foods, soil, and water1, 2
- Helps the body use calcium, magnesium, and vitamin D1, 2
- Calcium fructoborate studied for osteoarthritis symptoms1, 2
- No RDA; adult upper limit is 20 mg per day1, 2
What is Boron?
Boron never gets headline treatment, and perhaps that is fitting for a mineral whose job is mostly behind the scenes. It is not a structural building block like calcium; instead it nudges the metabolism of the minerals and hormones that are. The interesting human data centers on two areas: bone metabolism, where boron appears to reduce calcium and magnesium losses, and osteoarthritis, where a specific boron-carbohydrate compound — calcium fructoborate — has reduced pain and stiffness in several small trials.1
Where it comes from
Natural sources
- Widely distributed in plant foods: raisins, prunes, avocados, nuts, and legumes
- Present in soil and drinking water at varying levels
- Average adult intake estimated around 1 mg per day from food
How it's made
Supplements use boron citrate, glycinate, or calcium fructoborate forms.
What it does in products
Benefits
Bone health support
limited evidenceOsteoarthritis symptoms
limited evidenceSmall short-term trials of calcium fructoborate report changes in knee symptoms or inflammatory markers, but they do not establish boron as an osteoarthritis treatment.3, 4, 1
The studied compound is not interchangeable with every boron supplement, and the trials are too small for a confident effect estimate.
Hormone metabolism
insufficient evidenceEvidence scope and limitations
The review covers dietary boron, general boron supplements, and calcium fructoborate trials as distinct exposures.
- Boron has no established U.S. recommended dietary allowance and no clear clinical deficiency syndrome in humans.
- Most intervention studies are small, short, and use compounds that should not be treated as interchangeable.
Evidence last checked: 2026-09-26
Side effects & safety
Safety considerations
- Boron supplements are not recommended in pregnancy; stick to food sources. High-dose boric acid ingestion is toxic and particularly dangerous for infants.
- None well documented at typical supplemental doses.
- Not for: Kidney disease (boron is cleared by the kidneys)
- Not for: High-dose boric acid products should never be ingested
Amounts studied & product use
These figures describe research or common product use, not a personal dose or treatment recommendation.
In supplement studies and products
Small studies use different boron compounds and commonly supply roughly 3–6 mg elemental boron daily; calcium fructoborate trials report the compound mass separately. The U.S. adult upper limit is 20 mg daily, but no RDA or established treatment dose exists.
Regulatory status
- Dietary supplement under DSHEA. Boric acid and sodium borate are restricted as food additives; supplement forms (citrate, glycinate, fructoborate) are the standard.
Why boron appears in bone supplements
Boron's bone story is about retention, not construction. Human depletion studies found that a low-boron diet increased urinary losses of calcium and magnesium and reduced vitamin D levels — and that adding back just 3 mg per day reversed the effect. That mechanism makes boron a plausible supporting cast member alongside calcium, magnesium, and vitamin D, which is exactly how supplement makers position it. What is still missing is long-term evidence that boron itself reduces fracture risk, so treat it as a helper nutrient rather than a primary bone treatment.
1Frequently asked questions
How much boron do I need per day?
There is no official recommended dietary allowance for boron. Food intake averages about 1 mg daily; supplements typically provide 3–6 mg. The adult upper limit is 20 mg per day — staying under it is important because high doses are toxic.1, 2
The bottom line
Boron is biologically interesting but clinically under-established. Current evidence supports cautious language, not hormone or bone-treatment promises.
References
- Boron: Health Professional Fact Sheet. NIH Office of Dietary Supplements (2025) · government guidance
- Relationship between boron and magnesium status and bone mineral density: a review. Magnesium Research (1993) · other · PMID 8292503
- Calcium fructoborate and inflammation markers in adults with osteoarthritis: a pilot trial. Biological Trace Element Research (2011) · randomized trial · PMID 21607703
- Short-term efficacy of calcium fructoborate in adults with knee discomfort. Clinical Interventions in Aging (2014) · randomized trial · PMID 24940052
- Dietary Supplements. U.S. Food and Drug Administration (2025) · government guidance
Revision history
- Replaced search-result citations with exact sources, mapped claims to evidence, and reassessed evidence strength.